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Tracking a Deadly Virus

If you think that studying the deadly Ebola virus is all about donning a biohazard suit in a high-tech lab, think again. Check out these scientists from the National Institute of Allergy and Infectious...

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How Influenza Pandemics Occur

Credit: National Institute of Allergy and Infectious Diseases, NIH Flu season is upon us! Check out this NIH video to see how these pandemics emerge and spread new flu viruses around the globe.

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Promising Treatment for New Human Coronavirus

Caption: Transmission electron micrograph of novel coronavirusCredit: Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH In Fall 2012 a new coronavirus appeared on...

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Eradicating Ebola: In U.S. Biomedical Research, We Trust

Caption: Researcher inside a biosafety level 4 laboratory, which provides the necessary precautions for working with the Ebola virus.Credit: National Institute of Allergy and Infectious Diseases, NIH...

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Using Genomics to Follow the Path of Ebola

Caption: Colorized scanning electron micrograph of filamentous Ebola virus particles (blue) budding from a chronically infected VERO E6 cell (yellow-green).Credit: National Institute of Allergy and...

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Vaccine Research: New Tactics for Tackling HIV

Caption: Scanning electron micrograph of an HIV-infected immune cell.Credit: National Institute of Allergy and Infectious Diseases, NIH For many of the viruses that make people sick—think measles,...

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Snapshots of Life: New Target for Herpes Treatment?

Something about this image reminds me of that wacky and infectious old song: “It was a one-eyed, one-horned, flyin’ purple people eater …” Of course, this purple blob isn’t a people eater, but it does...

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Zika Virus: An Emerging Health Threat

Credit: Kraemer et al. eLife 2015;4:e08347 For decades, the mosquito-transmitted Zika virus was mainly seen in equatorial regions of Africa and Asia, where it caused a mild, flu-like illness and rash...

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Zika Vaccine: Two Candidates Show Promise in Mice

  Caption: Zika virus (red), isolated from a microcephaly case in Brazil. The virus is associated with cellular membranes in the center.Credit: NIAID Last February, the World Health Organization...

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Summer Reading Suggestions from Scientists: Robert Horvitz

Two Science Selections:  Horace Freeland Judson, Eighth Day of Creation. A comprehensive history of the origins and early science of the field of modern molecular biology, written by historian Horace...

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Feed a Virus, Starve a Bacterium?

Thinkstock/Stockbyte Yes, the season of colds and flu is coming. You’ve probably heard the old saying “feed a cold and starve a fever.” But is that sound advice? According to new evidence from mouse...

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Simplifying HIV Treatment: A Surprising New Lead

Caption: PET/CT imaging reveals a surprisingly high concentration (yellow, light green) of key immune cells called CD4 T cells in the colon (left) of an SIV-infected animal that received antibody...

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Snapshots of Life: Virus Hunting with Carbon Nanotubes

Credit: Penn State University The purple pods that you see in this scanning electron micrograph are the H5N2 avian flu virus, a costly threat to the poultry and egg industry and, in very rare...

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Creative Minds: Preparing for Future Pandemics

Jonathan Abraham / Credit: ChieYu Lin Growing up in Queens, NY, Jonathan Abraham developed a love for books and an interest in infectious diseases. One day Abraham got his hands on a copy of Laurie...

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Twinkle, Twinkle Little Cryo-EM Star

The stars are out and shining this holiday season. But there are some star-shaped structures now under study in the lab that also give us plenty of reason for hope. One of them is a tiny virus called...

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A Lean, Mean DNA Packaging Machine

Credit: Victor Padilla-Sanchez, The Catholic University of America, Washington, D.C. All plants and animals are susceptible to viral infections. But did you know that’s also true for bacteria? They get...

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Looking to Llamas for New Ways to Fight the Flu

Researchers are making tremendous strides toward developing better ways to reduce our risk of getting the flu. And one of the latest ideas for foiling the flu—a “gene mist” that could be sprayed into...

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Enlisting CRISPR in the Quest for an HIV Cure

Today, thanks to remarkable advances in antiretroviral drugs, most people with the human immunodeficiency virus (HIV) can expect to live an almost normal lifespan. But that means staying on...

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Uncovering a Hidden Zika Outbreak in Cuba

Credit: Sharon Isern, steampunkphage.com. When Brazilian health officials discovered four years ago that the mosquito-borne Zika virus could cause severe birth defects and other serious health...

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How Measles Leave the Body Prone to Future Infections

Credit: gettyimages/CHBD As a kid who was home-schooled on a Virginia farm in the 1950s, I wasn’t around other kids very much, and so didn’t get exposed to measles. And there was no vaccine yet. Later...

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Celebrating 2019 Biomedical Breakthroughs

Happy New Year! As we say goodbye to the Teens, let’s take a look back at 2019 and some of the groundbreaking scientific discoveries that closed out this remarkable decade. Each December, the...

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Structural Biology Points Way to Coronavirus Vaccine

Caption: Atomic-level structure of the spike protein of the virus that causes COVID-19. Credit: McLellan Lab, University of Texas at Austin The recent COVID-19 outbreak of a novel type of coronavirus...

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To Beat COVID-19, Social Distancing is a Must

gettyimages/SDI Productions Even in less challenging times, many of us try to avoid close contact with someone who is sneezing, coughing, or running a fever to avoid getting sick ourselves. Our...

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Bringing Needed Structure to COVID-19 Drug Development

Caption: Molecular map showing interaction between the spike protein (gold) of the novel coronavirus and the peptidase domain (blue) of human angiotensin-converting enzyme 2 (ACE2). Credit: Adapted...

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Capturing Viral Shedding in Action

Credit: Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT You’ve probably seen some amazing high-resolution images of SARS-CoV-2, the novel coronavirus...

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Finding New Ways to Fight Coronavirus … From Studying Bats

David Veesler/Credit: University of Washington Medicine, Seattle  David Veesler has spent nearly 20 years imaging in near-atomic detail the parts of various viruses, including coronaviruses, that...

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A Look Back at Science’s 2022 Breakthroughs

Credit: National Institute of Allergy and Infectious Diseases, NIH; Centers for Disease Control and Prevention; Shutterstock/tobe24, Midjourney Inc. Happy New Year! I hope everyone finished 2022 with...

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Study Reveals How Epstein-Barr Virus May Lead to Cancer

Caption: Illustration shows in the foreground EBNA1 protein (blue) bound to a preferred stretch of DNA. In the background, larger amounts of the protein accumulate, breaking strands of DNA, and...

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3D Animation Captures Viral Infection in Action

With the summer holiday season now in full swing, the blog will also swing into its annual August series. For most of the month, I will share with you just a small sampling of the colorful videos and...

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